TRAP-7

• Description :

  TRAP-7 is a thrombin receptor (PAR) activating peptide. TRAP-7 stimulates total inositol phosphate (IP) accumulation and phosphorylation of a specific endogenous substrate for activated PKC. TRAP-7 can be used in cardiovascular disease research[1].

• UNSPSC :

  12352209

• Hazard Statement :

  H315, H319, H335

• Target :

  Protease Activated Receptor (PAR)

• Type :

  Peptides

• Related Pathways :

  GPCR/G Protein

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/trap-7.html

• Purity :

  99.66

• Solubility :

  H2O : ≥ 100 mg/mL

• Smiles :

  OC[C@H](N)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(N)=O)C(N2[C@@H](CCC2)C(O)=O)=O)=O)=O)=O)=O)=O

• Molecular Formula :

  C39H63N11O10

• Molecular Weight :

  845.99

• Precautions :

  H315, H319, H335

• References & Citations :

  [1]Webb ML, et al. Effects of thrombin receptor activating peptide on phosphoinositide hydrolysis and protein kinase C activation in cultured rat aortic smooth muscle cells: evidence for "tethered-ligand" activation of smooth muscle cell thrombin receptors. Biochem Pharmacol. 1993 Apr 22;45 (8) :1577-82.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported

• CAS Number :

  [145229-76-1]