TRAP-14

• Description:

  TRAP-14 (SFLLRNPNDKYEPF) is a synthetic thrombin receptor agonist peptide.

• Product Name Alternative:

  SFLLRNPNDKYEPF

• UNSPSC:

  12352209

• Target:

  Thrombin

• Type:

  Peptides

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/trap-14.html

• Purity:

  99.94

• Solubility:

  H2O : ≥ 100 mg/mL

• Smiles:

  OC[C@H](N)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(N)=O)C(N2[C@@H](CCC2)C(N[C@@H](CC(N)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](CCC(O)=O)C(N3[C@@H](CCC3)C(N[C@H](C(O)=O)CC4=CC=CC=C4)=O)=O)=O)CC5=CC=C(C=C5)O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

• Molecular Formula:

  C81H118N20O23

• Molecular Weight:

  1739.92

• References & Citations:

  [1]Sugama Y, et al. Thrombin receptor 14-amino acid peptide mediates endothelial hyperadhesivity and neutrophil adhesion by P-selectin-dependent mechanism. Circ Res. 1992 Oct;71 (4) :1015-9.|[2]Sabo T, et al. Structure-activity studies of the thrombin receptor activating peptide. Biochem Biophys Res Commun. 1992 Oct 30;188 (2) :604-10.|[3]Maruyama Y, et al. Thrombin receptor agonist peptide decreases thrombomodulin activity in cultured human umbilical vein endothelial cells. Biochem Biophys Res Commun. 1994 Mar 30;199 (3) :1262-9.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported

• CAS Number:

  [137339-65-2]