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TRAP-6

CAT: 0804-HY-P0078-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-P0078-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TRAP-6 (PAR-1 agonist peptide), a peptide fragment, is a selective protease activating receptor 1 (PAR1) agonist. TRAP-6 activates human platelets via the thrombin receptor. TRAP-6 shows no activity at PAR4[1].
CAS Number
[141136-83-6]
Product Name Alternative
PAR-1 agonist peptide; Thrombin Receptor Activator Peptide 6
UNSPSC
12352209
Hazard Statement
H302, H315, H319, H335
Target
Protease Activated Receptor (PAR)
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/TRAP-6.html
Purity
99.98
Solubility
H2O : 25 mg/mL (ultrasonic)
Smiles
O=C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(O)=O)CC(N)=O)=O)=O)=O)[C@@H](NC([C@@H](N)CO)=O)CC1=CC=CC=C1
Molecular Formula
C34H56N10O9
Molecular Weight
748.87
Precautions
H302, H315, H319, H335
References & Citations
[1]Kahn ML, et, al. Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin. J Clin Invest. 1999 Mar;103 (6) :879-87.|[2]Kinlough-Rathbone RL, et, al. Rabbit and rat platelets do not respond to thrombin receptor peptides that activate human platelets. Blood. 1993 Jul 1;82 (1) :103-6.|[3]Chintala MS, et, al. Disparate effects of thrombin receptor activating peptide on platelets and peripheral vasculature in rats. Eur J Pharmacol. 1998 May 22;349 (2-3) :237-43.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
PAR1

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