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SB-429201

CAT: 0804-HY-119017-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-119017-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SB-429201 is a potent and selective HDAC1 (IC50~1.5 μM) . SB-429201 displays at least a 20-fold preference for HDAC1 inhibition over HDAC3 and HDAC8[1][2].
CAS Number
1027971-34-1
Product Name Alternative
MK-0869; MK-869; L-754030
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sb-429201.html
Purity
98.15
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC=C(C(NC2=CC=C(OC3=CC=CC=C3)C=C2)=O)C=C1)CCC4=CC=CC=C4
Molecular Formula
C28H24N2O3
Molecular Weight
436.50
References & Citations
[1]Bieliauskas AV, Pflum MK. Isoform-selective histone deacetylase inhibitors. Chem Soc Rev. 2008;37 (7) :1402-1413. |[2]Hu E, et al. Identification of novel isoform-selective inhibitors within class I histone deacetylases. J Pharmacol Exp Ther. 2003;307 (2) :720-728.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC3

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