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HER2-IN-16

CAT: 0804-HY-163420Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-163420Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HER2-IN-16 (Compound 14) is an inhibitor for HER2, which inhibits the Her YVMA exon 20 insertion mutation (HER2 YVMA) with an IC50 IC50 [1].
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/her2-in-16.html
Solubility
10 mM in DMSO
Smiles
C=CC(NC1CN(C1)C2=C3C(NC4=CC(C)=C(C=C4)OC5=CC6=NC=NN6C=C5)=NC=NN3C=C2)=O
Molecular Formula
C25H23N9O2
Molecular Weight
481.51
References & Citations
[1]Svitlana KULYK, et al., Compounds and methods for modulating her2. Patent WO2024044570.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ErbB2/HER2

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