HER2-IN-16
CAT:
804-HY-163420
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
HER2-IN-16
- UNSPSC Description: HER2-IN-16 (Compound 14) is an inhibitor for HER2, which inhibits the Her YVMA exon 20 insertion mutation (HER2 YVMA) with an IC50 IC50 [1].
- Target Antigen: EGFR
- Type: Reference compound
- Related Pathways: JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/her2-in-16.html
- Solubility: 10 mM in DMSO
- Smiles: C=CC(NC1CN(C1)C2=C3C(NC4=CC(C)=C(C=C4)OC5=CC6=NC=NN6C=C5)=NC=NN3C=C2)=O
- Molecular Weight: 481.51
- References & Citations: [1]Svitlana KULYK, et al., Compounds and methods for modulating her2. Patent WO2024044570.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported