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PAT-494

CAT: 0804-HY-126230Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-126230Size:1 Each
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Description
PAT-494 is an ATX inhibitor with significant activity in biochemical and plasma assays. PAT-494 can reduce LPA levels in rat plasma through oral administration. The structure-activity relationship study of PAT-494 shows that its binding mode with ATX is novel and it can effectively occupy the hydrophobic pockets and channels of ATX[1].
CAS Number
1781233-84-8
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/pat-494.html
Smiles
O=C1NC(N2CC3=C(C4=CC=CC=C4N3CC5=CC=C(F)C=C5)C[C@@H]21)=O
Molecular Formula
C20H16FN3O2
Molecular Weight
349.36
References & Citations
[1]Discovery, Structure-Activity Relationship, and Binding Mode of an Imidazo[1,2-a]pyridine Series of Autotaxin Inhibitors
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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