PAT-IN-2

• Description :

  PAT-IN-2 is a protein acyl transferases (PAT) inhibitor. PAT-IN-2 competitively inhibits Erf2 autopalmitoylation (WO2017011518A1; compound 25) [1].

• CAS Number :

  [2066572-01-6]

• UNSPSC :

  12352005

• Target :

  Ras

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; MAPK/ERK Pathway

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/pat-in-2.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC(C1=CC=C(C=C1)CC(C)C)CN(CCN(C2)CCCC[C@@H]3N(CCNC3)CCC4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)[C@H]2CC5=CC=C(C=C5)O

• Molecular Formula :

  C42H56F6N4O

• Molecular Weight :

  746.91

• References & Citations :

  [1]Robert Joseph DESCHENES, et al. Protein acyl transferase inhibitors and methods of treatment. WO2017011518A1.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported