PAT-IN-2

• Description:

  PAT-IN-2 is a protein acyl transferases (PAT) inhibitor. PAT-IN-2 competitively inhibits Erf2 autopalmitoylation (WO2017011518A1; compound 25) [1].

• UNSPSC:

  12352005

• Target:

  Ras

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; MAPK/ERK Pathway

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/pat-in-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(C1=CC=C(C=C1)CC(C)C)CN(CCN(C2)CCCC[C@@H]3N(CCNC3)CCC4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)[C@H]2CC5=CC=C(C=C5)O

• Molecular Formula:

  C42H56F6N4O

• Molecular Weight:

  746.91

• References & Citations:

  [1]Robert Joseph DESCHENES, et al. Protein acyl transferase inhibitors and methods of treatment. WO2017011518A1.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2066572-01-6]