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2-PAT

CAT: 0804-HY-143438Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-143438Size:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
2-PAT, an analogue of Rasagiline and Selegiline, a reversible MAO-A inhibitor with an IC50 of 0.721 μM. 2-PAT is an inactivator of MAO-B with an IC50 of 14.6 μM. 2-PAT has the potential for Parkinson’s disease and depression research[1]. 2-PAT is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
[134467-58-6]
UNSPSC
12352005
Target
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/2-pat.html
Solubility
10 mM in DMSO
Smiles
C#CCNC1CC2=C(C=CC=C2)CC1
Molecular Formula
C13H15N
Molecular Weight
185.26
References & Citations
[1]Letitia Meiring, et al. The evaluation of N-propargylamine-2-aminotetralin as an inhibitor of monoamine oxidase. Bioorg Med Chem Lett. 2022 Jul 1;67:128746.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAO-A; MAO-B

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