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YM-16638

CAT: 0804-HY-19042-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-19042-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
YM-16638 is an orally active leukotriene (LT) antagonist. YM-16638 can inhibit the production of LTC4, LTD4, and LTE4 in guinea pig trachea, with IC50 values of 0.05 μM, 0.16 μM, and 0.096 μM, respectively. YM-16638 has a dose-dependent inhibitory effect on antigen-induced early and late respiratory responses in allergic sheep[1].
CAS Number
104073-72-5
Product Name Alternative
YM 638
UNSPSC
12352005
Target
Leukotriene Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ym-16638.html
Smiles
O=C(O)CSC1=NN=C(SCCCOC2=CC=C(C(C)=O)C(O)=C2CCC)S1
Molecular Formula
C18H22N2O5S3
Molecular Weight
442.57
References & Citations
[1]Tomioka K, et al. The effect of an orally active leukotriene (LT) antagonist YM-16638 on antigen-induced early and late airway responses in allergic sheep. Prostaglandins Leukot Essent Fatty Acids. 1989 Apr;36 (1) :43-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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