YM-17690

• UNSPSC Description:

  YM-17690 is a LTD4 and LTE4 agonist, with a pKi value of 9.28 for [3H]LTD4. It induces dose-dependent contractions in guinea pig ileum, lung parenchyma, and trachea, with EC50 values of 16, 3.9, and 22 nM, respectively. YM-17690 can be used in research related to asthma and inflammation[1].

• Target Antigen:

  Leukotriene Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/ym-17690.html

• Smiles:

  O=C(O)CCC1=CC=C(OCC(O)=O)C(NC(C2=CC=C(OCCCCC3=CC=CC=C3)C=C2)=O)=C1

• Molecular Weight:

  491.53

• References & Citations:

  [1]Tomioka K, et al. Isolated tissue and binding studies of YM-17690, a novel and non-analogous leukotriene agonist. J Pharm Pharmacol. 1987 Oct;39(10):819-24.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  108806-41-3