YM-17690

• Description :

  YM-17690 is a LTD4 and LTE4 agonist, with a pKi value of 9.28 for [3H]LTD4. It induces dose-dependent contractions in guinea pig ileum, lung parenchyma, and trachea, with EC50 values of 16, 3.9, and 22 nM, respectively. YM-17690 can be used in research related to asthma and inflammation[1].

• CAS Number :

  [108806-41-3]

• UNSPSC :

  12352005

• Target :

  Leukotriene Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/ym-17690.html

• Smiles :

  O=C(O)CCC1=CC=C(OCC(O)=O)C(NC(C2=CC=C(OCCCCC3=CC=CC=C3)C=C2)=O)=C1

• Molecular Formula :

  C28H29NO7

• Molecular Weight :

  491.53

• References & Citations :

  [1]Tomioka K, et al. Isolated tissue and binding studies of YM-17690, a novel and non-analogous leukotriene agonist. J Pharm Pharmacol. 1987 Oct;39 (10) :819-24.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported