YM-430

CAT: 0804-HY-19115Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-19115Size:1 Each
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Description
YM-430 is an oral active calcium entry-blocking and beta-adrenoceptor-blocking agent. YM-430 inhibits Amifampridine (HY-14946) -induced rhythmic contractions with an IC50 value of 59.2 nM and inhibits arginine vasopressin-induced ST-segment depression with an IC50 value of 36.6 mg/kg. YM-430 can be used for study of angina pectoris[1].
CAS Number
[153192-22-4]
UNSPSC
12352005
Target
Adrenergic Receptor; Calcium Channel
Type
Reference compound
Related Pathways
GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ym-430.html
Smiles
O=C(C1=C(C)NC(C)=C(C(OC)=O)[C@@H]1C2=CC=CC([N+]([O-])=O)=C2)OCCCCNC[C@H](O)COC3=CC=CC=C3
Molecular Formula
C29H35N3O8
Molecular Weight
553.60
References & Citations
[1]Shibasaki K, et al. Antianginal effects of YM430, a novel calcium entry-blocking and beta-adrenoceptor-blocking agent in several experimental angina models. Gen Pharmacol. 1997;29 (4) :545-550.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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