T-1095

• UNSPSC Description:

  T-1095 is a selective and orally active Na+-glucose cotransporter (SGLT) inhibitor with IC50s of 22.8 μM and 2.3 μM for human SGLT1 and SGLT2, respectively. T-1095 can be used for diabetes research[1].

• Target Antigen:

  SGLT

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/t-1095.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C(C(O)=C1)=C(C=C1C)O[C@@H]([C@@H]([C@H]2O)O)O[C@@H]([C@H]2O)COC(OC)=O)CCC3=CC=C4C(C=CO4)=C3

• Molecular Weight:

  516.49

• References & Citations:

  [1]A Oku, et al. T-1095, an inhibitor of renal Na+-glucose cotransporters, may provide a novel approach to treating diabetes. Diabetes. 1999 Sep;48(9):1794-800.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Phase 2

• CAS Number:

  209746-59-8