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AChE/Aβ-IN-6

CAT: 0804-HY-159151Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-159151Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BACE1-IN-15 (compound 4j) is a potent inhibitor of BACE1 (β-secretase) that can inhibited the copper ion induced Aβ toxicity, with the EC50 of 0.68 μM[1].
UNSPSC
12352005
Target
Amyloid-β; Beta-secretase
Type
Reference compound
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-aβ-in-6.html
Smiles
O=C(NCC1=CN(CC2=CC=C(C(F)(F)F)C=C2)N=N1)/C=C/C3=CC=CC=C3
Molecular Formula
C20H17F3N4O
Molecular Weight
386.37
References & Citations
[1]Lin-Jie Tan, et al. Discovery of cinnamamide/ester triazole hybrids as potential treatment for Alzheimer’s disease. Bioorganic Chemistry Volume 150, September 2024, 107584.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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