hCAIX-IN-22

hCAIX-IN-22

• UNSPSC Description: hCAIX-IN-22 is a highly selective inhibitor of human carbonic anhydrase (hCA) isoform XII (Ki=9.7 nM) with anticancer activity[1].
• Target Antigen: Carbonic Anhydrase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/hcaix-in-22.html
• Smiles: O=S(C1=CC=C(N/N=C(N(CC)C/2=O)\SC2=C3C(NC4=C/3C=C(Br)C=C4)=O)C=C1)(N)=O
• Molecular Weight: 522.40
• References & Citations: [1]Secci, et al. "New Structural Features of Isatin Dihydrothiazole Hybrids for Selective Carbonic Anhydrase Inhibitors." ACS Medicinal Chemistry Letters (2024).
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported