PKC gamma Recombinant Rabbit Monoclonal Antibody [JG69-32]

PKC gamma Recombinant Rabbit Monoclonal Antibody [JG69-32]

• Description: Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions, including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes, including conventional (c) PKC isoforms (α, βI, βII and γ) and novel (n) PKC isoforms (δ, ε, ζ, η, θ, λ/ι, µ and ν). Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of PKC δ and ε are independent of Ca2+. On the other hand, most of the other PKC members possess phorbol ester-binding activities and kinase activities.
• Product Name Alternative: KPCG_HUMAN antibody MGC57564 antibody OTTHUMP00000067291 antibody PKC-gamma antibody PKCC antibody PKCG antibody PRKCG antibody Protein kinase C gamma antibody Protein kinase C gamma polypeptide antibody Protein kinase C gamma type antibody Protein kinase C, gamma antibody SCA 14 antibody SCA14 antibody
• Abbreviation: PKC-gamma, PRKCG, PKCG
• CAS Number: 9000-83-3
• Swiss Prot: P05129 Human, P63318 Mouse, P63319 Rat
• Cellular Locus: Cell membrane. Cytoplasm.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Recombinant protein within Human PKC gamma aa 564-697 / 697.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IHC-P
• Positive Control: A549 cell lysates, rat cerebellum tissue, mouse cerebellum tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500-1:2,000 ;IHC-P: 1:1,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 78 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes