gamma Sarcoglycan Recombinant Rabbit Monoclonal Antibody [JA11-57]

gamma Sarcoglycan Recombinant Rabbit Monoclonal Antibody [JA11-57]

• Description: The sarcoglycan transmembrane proteins are members of the dystrophin complex. Sarcoglycans cluster together to form a complex, which is localized in the cell membrane of skeletal, cardiac and smooth muscle fibers. Four sarcoglycan subunit proteins, designated α-, β-, γ- and δ-sarcoglycan, form a complex on the skeletal muscle cell surface membrane. A genetic defect in any one of these proteins causes the loss or marked decrease of the whole sarcoglycan complex, which is observed in the autosomal recessive muscular dystrophy, sarcoglycanopathy. In smooth muscle, β- and δ-sarcoglycans are associated with ε-sarcoglycan, a glycoprotein homologous to α-sarcoglycan. Additionally, a complete deficiency in δ-sarcoglycan is the cause of the Syrian hamster BIO.14 cardiomyopathy.
• Product Name Alternative: 35 kDa dystrophin associated glycoprotein antibody 35 kDa dystrophin-associated glycoprotein antibody 35DAG antibody 35kD dystrophin associated glycoprotein antibody 35kDa dystrophin-associated glycoprotein antibody A4 antibody DAGA4 antibody DMDA antibody DMDA1 antibody Gamma SG antibody Gamma-sarcoglycan antibody Gamma-SG antibody LGMD2C antibody MAM antibody MGC130048 antibody Sarcoglycan gamma antibody SCARMD2 antibody SCG3 antibody SGCG antibody SGCG_HUMAN antibody TYPE antibody
• Abbreviation: Gamma-SG, 35DAG, SGCG
• CAS Number: 9000-83-3
• Swiss Prot: Q13326 Human
• Cellular Locus: Cell membrane. Cytoplasm.
• Host: Rabbit
• Species Reactivity: Human, Mouse
• Immunogen: Recombinant protein within Human gamma Sarcoglycan aa 42-291 / 291.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IP, IHC-P
• Positive Control: Human skeletal muscle tissue lysates, human striated muscle tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500-1:2,000 ;IHC-P: 1:50-1:200 ;IP: Use at an assay dependent concentration.
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 32 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes