Interferon gamma Recombinant Rabbit Monoclonal Antibody [JM10-10]

Interferon gamma Recombinant Rabbit Monoclonal Antibody [JM10-10]

• Description: Interferon gamma (IFN-γ) is a dimerized soluble cytokine that is the only member of the type II class of interferons. In humans, the IFN-γ protein is encoded by the IFNG gene. IFN-γ, or type II interferon, is a cytokine that is critical for innate and adaptive immunity against viral, some bacterial and protozoan infections. IFN-γ is an important activator of macrophages and inducer of major histocompatibility complex class II molecule expression. Aberrant IFN-γ expression is associated with a number of autoinflammatory and autoimmune diseases. The importance of IFN-γ in the immune system stems in part from its ability to inhibit viral replication directly, and most importantly from its immunostimulatory and immunomodulatory effects. IFN-γ is produced predominantly by natural killer cells (NK) and natural killer T cells (NKT) as part of the innate immune response, and by CD4 Th1 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops as part of the adaptive immune response. IFN-γ is also produced by non-cytotoxic innate lymphoid cells (ILC), a family of immune cells first discovered in the early 2010s.
• Product Name Alternative: IFG antibody IFI antibody IFN gamma antibody IFN, immune antibody IFN-gamma antibody IFNG antibody IFNG_HUMAN antibody Immune interferon antibody Interferon gamma antibody
• Abbreviation: IFN-gamma, IFNG
• CAS Number: 9000-83-3
• Swiss Prot: P01579 Human
• Cellular Locus: Secreted.
• Host: Rabbit
• Species Reactivity: Human
• Immunogen: Synthetic peptide within N-terminal human Interferon gamma.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, FC
• Positive Control: Human IFN-gamma recombinant protein, Jurkat.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000 ;FC: 1:50-1:100
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 19 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes