gamma Synuclein Recombinant Rabbit Monoclonal Antibody [JM90-32]

gamma Synuclein Recombinant Rabbit Monoclonal Antibody [JM90-32]

• Description: Gamma-synuclein is a protein that in humans is encoded by the SNCG gene. Synuclein-gamma is a member of the synuclein family of proteins, which are believed to be involved in the pathogenesis of neurodegenerative diseases. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development. Gamma-synuclein is a synuclein protein found primarily in the peripheral nervous system (in primary sensory neurons, sympathetic neurons, and motor neurons) and retina. It is also detected in the brain, ovarian tumors, and in the olfactory epithelium. Gamma-synuclein is the least conserved of the synuclein proteins. Gamma-Synucleins expression in breast tumors is a marker for tumor progression as mammalian gamma-synuclein was first identified as breast cancer-specific gene 1 (BCSG1). A change in the expression of gamma-synuclein has been observed in the retina of patients with Alzheimer's disease. The normal cellular function of gamma-synuclein remains unknown.
• Product Name Alternative: BCSG1 antibody Breast cancer specific gene 1 protein antibody Breast cancer specific protein 1 antibody Breast cancer-specific gene 1 protein antibody Gamma synuclein antibody Gamma-synuclein antibody Persyn antibody PRSN antibody SNCG antibody SR antibody Synoretin antibody Synuclein gamma antibody synuclein, gamma (breast cancer-specific protein 1) antibody SYUG_HUMAN antibody
• Abbreviation: SR, SNCG, BCSG1, PERSYN, PRSN
• CAS Number: 9000-83-3
• Swiss Prot: O76070 Human, Q63544 Rat
• Cellular Locus: Cytoplasm. Cytoskeleton. Centrosome.
• Host: Rabbit
• Species Reactivity: Human, Rat
• Immunogen: Synthetic peptide within Human gamma Synuclein aa 78-127 / 127.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, IHC-P, FC, IP
• Positive Control: Rat kidney tissue lysates, Hela, rat brain tissue, human lung tissue, human breast tissue, rat bladder tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500-1:2,000;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:1,000;FC: 1:50-1:100;IP: Use at an assay dependent concentration.
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 13 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes