GPX4-IN-12
CAT:
804-HY-162718
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
GPX4-IN-12
- CAS Number: 931704-14-2
- UNSPSC Description: GPX4-IN-12 (compound I22) is a non-covalent GPX4 inhibitor. GPX4-IN-12 induces ferroptosis and inhibits cell growth of HT1080 cells[1].
- Target Antigen: Ferroptosis
- Type: Reference compound
- Related Pathways: Apoptosis
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/gpx4-in-12.html
- Smiles: N#CC1=C(NCCCN2C=CN=C2)OC(C3=CC=C(O3)COC4=CC=CC=C4)=N1
- Molecular Weight: 389.41
- References & Citations: [1]Huang W, et al. Ferroptosis-inducing compounds synergize with docetaxel to overcome chemoresistance in docetaxel-resistant non-small cell lung cancer cells. Eur J Med Chem. 2024 Jul 10;276:116670.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported