GPX4-IN-10
CAT:
804-HY-162716
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
GPX4-IN-10
- UNSPSC Description: GPX4-IN-10 (compound I20) is a non-covalent GPX4 inhibitor. GPX4-IN-10 induces ferroptosis and inhibits cell growth of HT1080 cells[1].
- Target Antigen: Ferroptosis
- Type: Reference compound
- Related Pathways: Apoptosis
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/gpx4-in-10.html
- Smiles: CC1CCN(CC2=CC=C(NC(CN3C(C)=C(C(N(C4=CC=CC=C4)N=C5)=O)C5=C3C)=O)C=C2)CC1
- Molecular Weight: 483.60
- References & Citations: [1]Huang W, et al. Ferroptosis-inducing compounds synergize with docetaxel to overcome chemoresistance in docetaxel-resistant non-small cell lung cancer cells. Eur J Med Chem. 2024 Jul 10;276:116670.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported