Products for Research Use Only
RegisterLogin

GPX4-IN-9

CAT: 0804-HY-157762-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-157762-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
GPX4-IN-9 (Compound A16) is a glutathione peroxidase 4 (GPX4) inhibitor that specifically targets GPX4 under both in vitro and in vivo conditions, inducing ferroptosis. GPX4-IN-9 exhibits cytotoxicity against pancreatic cancer cells and can be used in cancer research[1].
CAS Number
3032746-99-6
UNSPSC
12352005
Target
Ferroptosis; Glutathione Peroxidase
Type
Reference compound
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gpx4-in-9.html
Purity
99.18
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=S(C(C=C1)=CC=C1CN(C2=CC=C(C=C2)C3=NC4=C(S3)C=CC=C4)CC#C)(N(C#C)C)=O
Molecular Formula
C26H21N3O2S2
Molecular Weight
471.59
References & Citations
[1]Tang Z, et al. Novel Covalent Probe Selectively Targeting Glutathione Peroxidase 4 In Vivo: Potential Applications in PancrTang Z, et al. Novel Covalent Probe Selectively Targeting Glutathione Peroxidase 4 In Vivo: Potential Applications in Pancreatic Cancer Therapy. J Med Chem. 2024 Feb 8;67 (3) :1872-1887.eatic Cancer Therapy. J Med Chem. 2024 Feb 8;67 (3) :1872-1887.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
GPX4

Related Products

CatalogName
HY-163995-01GPX4-IN-13
HY-149923-01GPX4-IN-4
HY-138556-01GPX4-IN-2
HY-162716GPX4-IN-10
HY-155663-01GPX4-IN-5
HY-141809-01GPX4-IN-3
HY-176220GPX4-AUTAC
HY-162717GPX4-IN-11
HY-162718GPX4-IN-12
HY-175041GPX4-IN-18

Alternative Products

CatalogName
GTR19262262-01GPX4-IN-9
P45367GPX4
BA3428-100GPX4-IN-6
BA3420-10GPX4-IN-5
BA3452-1GPX4-IN-2
70R-17589GPX4 antibody
T88965-01GPX4-IN-11
509990GPX4 discontinued
564210-01GPX4 (Biotin)
MBS5821438GPX4-IN-7

Popular Products