α-Amylase/α-Glucosidase-IN-12

α-Amylase/α-Glucosidase-IN-12

• UNSPSC Description: α-Amylase/α-Glucosidase-IN-12 (compound 10k) is a dual inhibitor targeting α-glucosidase and α-amylase with IC50 of 34.52 nM and 24.62 nM, respectively. α-Amylase/α-Glucosidase-IN-12 is an inhibitor designed based on triazolo[4,3-b][1,2,4]triazine and has the potential to be used in diabetes research[1].
• Target Antigen: Amylases; Glycosidase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-sugar/lipid metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/α-amylase-α-glucosidase-in-12.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(NC1=CC=C(C(F)(F)F)C=C1)CSC2=NN=C3N2N=C(C4=CC=CC=C4)C=N3
• Molecular Weight: 430.41
• References & Citations: [1]Seyfi S, et al. Synthesis, biological activities, and molecular docking studies of triazolo[4,3-b]triazine derivatives as a novel class of α-glucosidase and α-amylase inhibitors. Arch Pharm (Weinheim). 2024 Mar 19:e2300628.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported