α-Amylase/α-Glucosidase-IN-4

• UNSPSC Description:

  α-Amylase/α-Glucosidase-IN-4 (compound 5) is a dual inhibitor of α-glucosidase (Glucosidase) and α-amylase (Amylases) with IC50s of 0.15 μM and 1.10 μM, respectively. α-Amylase/α-Glucosidase-IN-4 has potential antidiabetic activity[1].

• Target Antigen:

  Amylases; Glycosidase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/α-amylase-α-glucosidase-in-4.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(OCC)C1=C(NC2=CC=C([N+]([O-])=O)C=C2)CC(N(C3=CC=C([N+]([O-])=O)C=C3)C1C4=CC=CC([N+]([O-])=O)=C4)C5=CC([N+]([O-])=O)=CC=C5

• Molecular Weight:

  654.58

• References & Citations:

  [1]Saleem F, et al. Multicomponent diastereoselective synthesis of tetrahydropyridines as α-amylase and α-glucosidase enzymes inhibitors. Future Med Chem. 2023 Aug 31.. .

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported