α-Amylase/α-Glucosidase-IN-2
CAT:
804-HY-146225
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
α-Amylase/α-Glucosidase-IN-2
- CAS Number: 2446063-14-3
- UNSPSC Description: α-Amylase/α-Glucosidase-IN-2 (compound 5) is a potent α-amylase and α-glucosidase dual inhibitor with IC50 values of 13.02, 13.09 µM for α-amylase and α-glucosidase, respectively. α-Amylase/α-Glucosidase-IN-2 has the potential for the research of diabetic complications[1].
- Target Antigen: Glycosidase
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Metabolism-sugar/lipid metabolism
- Field of Research: Metabolic Disease
- Assay Protocol: https://www.medchemexpress.com/α-amylase-α-glucosidase-in-2.html
- Solubility: 10 mM in DMSO
- Smiles: ClC1=CC=C(C=C1)/C=N/NC2=NC(C3=CC=CC=C3)=C(C4=CC=CC=C4)N=N2
- Molecular Weight: 385.85
- References & Citations: [1]Shamim S, et al. Synthesis and screening of (E)-3-(2-benzylidenehydrazinyl)-5,6-diphenyl-1,2,4-triazine analogs as novel dual inhibitors of α-amylase and α-glucosidase. Bioorg Chem. 2020 Aug;101:103979.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported