α-Amylase/α-Glucosidase-IN-11 | Gentaur

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Alternative Products

Cat	Name
T61706-1mg	α-Amylase/α-Glucosidase-IN-2
T60255-10mg	α-Amylase/α-Glucosidase-IN-1
T60255-1g	α-Amylase/α-Glucosidase-IN-1
T61706-1g	α-Amylase/α-Glucosidase-IN-2
T60255-1mg	α-Amylase/α-Glucosidase-IN-1
T60255-5mg	α-Amylase/α-Glucosidase-IN-1
T61706-10mg	α-Amylase/α-Glucosidase-IN-2
T61706-50mg	α-Amylase/α-Glucosidase-IN-2
T61706-5mg	α-Amylase/α-Glucosidase-IN-2
T60255-50mg	α-Amylase/α-Glucosidase-IN-1

α-Amylase/α-Glucosidase-IN-11

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804-HY-162390

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α-Amylase/α-Glucosidase-IN-11

UNSPSC Description: α-Amylase/α-Glucosidase-IN-11 (Compound 5d) is a isoxazolidine-isatin hybrid with significant antidiabetic activity. α-Amylase/α-Glucosidase-IN-11 competitively inhibits α-amylase (IC50 = 30.39 μM) and α-glucosidase (IC50 = 65.1 μM), two key digestive enzymes. α-Amylase/α-Glucosidase-IN-11 does not cross the blood-brain barrier[1].
Target Antigen: Amylases; Glycosidase
Type: Reference compound
Related Pathways: Metabolic Enzyme/Protease
Applications: Metabolism-sugar/lipid metabolism
Field of Research: Endocrinology
Assay Protocol: https://www.medchemexpress.com/α-amylase-α-glucosidase-in-11.html
Solubility: 10 mM in DMSO
Smiles: O=C(N/N=C1C(NC2=C\1C=CC=C2Cl)=O)COC3=C(C)C=CC=C3C[C@@H]4C[C@]5([H])N([C@]6(N(C)C5=O)[C@H](C(C)C)CC[C@@H](C)C6)O4
Molecular Weight: 622.15
References & Citations: [1]Ghannay S, et al. dentification of dual-target isoxazolidine-isatin hybrids with antidiabetic potential: Design, synthesis, in vitro and multiscale molecular modeling approaches. Heliyon. 2024 Feb 11;10(4):e25911.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

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