α-Amylase/α-Glucosidase-IN-3

• UNSPSC Description:

  α-Amylase/α-Glucosidase-IN-3 (Compound 17) is an α-Amylase/α-Glucosidase dual inhibitor, with IC50s of 0.70 μM and 1.10 μM. α-Amylase/α-Glucosidase-IN-3 can be used for research of type-II diabetes mellitus[1].

• Target Antigen:

  Amylases; Glycosidase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/α-amylase-α-glucosidase-in-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=[N+](C1=CC=C(C2=NN=C(SC/C(C3=CC(Cl)=C(Cl)C=C3)=N/N=C/C4=CC(Cl)=C(Cl)C=C4)N2)C=C1)[O-]

• Molecular Weight:

  580.27

• References & Citations:

  [1]Khan I, et al. Synthesis and In Vitro α-Amylase and α-Glucosidase Dual Inhibitory Activities of 1,2,4-Triazole-Bearing bis-Hydrazone Derivatives and Their Molecular Docking Study. ACS Omega. 2023 Jun 5;8(25):22508-22522.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported