α-Amylase/α-Glucosidase-IN-3

α-Amylase/α-Glucosidase-IN-3

• UNSPSC Description: α-Amylase/α-Glucosidase-IN-3 (Compound 17) is an α-Amylase/α-Glucosidase dual inhibitor, with IC50s of 0.70 μM and 1.10 μM. α-Amylase/α-Glucosidase-IN-3 can be used for research of type-II diabetes mellitus[1].
• Target Antigen: Amylases; Glycosidase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-sugar/lipid metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/α-amylase-α-glucosidase-in-3.html
• Solubility: 10 mM in DMSO
• Smiles: O=[N+](C1=CC=C(C2=NN=C(SC/C(C3=CC(Cl)=C(Cl)C=C3)=N/N=C/C4=CC(Cl)=C(Cl)C=C4)N2)C=C1)[O-]
• Molecular Weight: 580.27
• References & Citations: [1]Khan I, et al. Synthesis and In Vitro α-Amylase and α-Glucosidase Dual Inhibitory Activities of 1,2,4-Triazole-Bearing bis-Hydrazone Derivatives and Their Molecular Docking Study. ACS Omega. 2023 Jun 5;8(25):22508-22522.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported