α-Amylase/α-Glucosidase-IN-6

• UNSPSC Description:

  α-Amylase/α-Glucosidase-IN-6 (compound 5j) is a potent dual inhibitor of α-amylase and α-glucosidase, with IC50s of 17.0 and 40.1 µM, respectively. α-Amylase/α-Glucosidase-IN-6 exhibits anti-hyperglycemic activities[1].

• Target Antigen:

  Amylases; Glycosidase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/α-amylase-α-glucosidase-in-6.html

• Solubility:

  10 mM in DMSO

• Smiles:

  ClC1=CC=CC=C1C2=NOC(COC3=NC4=CC=C(OC)C=C4N=C3NCC)=C2

• Molecular Weight:

  410.85

• References & Citations:

  [1]Phongphane L, et, al. Synthesis, biological evaluation, and molecular modelling of novel quinoxaline-isoxazole hybrid as anti-hyperglycemic. Comput Biol Chem. 2023 Oct:106:107938.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported