EZH2-IN-21

EZH2-IN-21

• CAS Number: 923894-97-7
• UNSPSC Description: EZH2-IN-21 is a potent inhibitor of the histone lysine methyltransferase enhancer of zeste homologue 2 (EZH2) with anticancer activity. EZH2-IN-21 is competitive with the cofactor SAM and noncompetitive with peptide or nucleosome substrates[1].
• Target Antigen: Histone Methyltransferase
• Type: Reference compound
• Related Pathways: Epigenetics
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/ezh2-in-21.html
• Smiles: O=C(C1=CC(C2CC2)=NC3=C1C=NN3C(C)C)NCC4=C(C)C=C(C)NC4=O
• Molecular Weight: 379.46
• References & Citations: [1]Verma SK, et al. Identification of Potent, Selective, Cell-Active Inhibitors of the Histone Lysine Methyltransferase EZH2. ACS Med Chem Lett. 2012 Oct 19;3(12):1091-6.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported