EZH2-AF647

• Description :

  EZH2-AF647 is a fluorescent probe derived from UNC2239 that improves receptor TR-FRET properties by using Alexa 647 dye[1].

• UNSPSC :

  12171500

• Target :

  Fluorescent Dye

• Type :

  Dye Reagents

• Related Pathways :

  Others

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/ezh2-af647.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC(N1)=CC(CCC)=C(CNC(C2=C(C=NN3C(C)C)C3=CC(C4=CC=C(N5CCN(CCCCNC(CCCCCN6C7=CC=C(S(=O)([O-])=O)C=C7C(C)(C)/C6=C/C=C/C=C/C8=[N+](CCOC)C9=CC=C(S(=O)(O)=O)C=C9C8(C)C)=O)CC5)N=C4)=C2)=O)C1=O

• Molecular Formula :

  C68H86N10O10S2

• Molecular Weight :

  1267.60

• References & Citations :

  [1]Falkenstern L, et al., A miniaturized mode-of-action profiling platform enables high throughput characterization of the molecular and cellular dynamics of EZH2 inhibition. Sci Rep. 2024 Jan 19;14 (1) :1739.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Dye Reagents

• Clinical Information :

  No Development Reported