EZH2-AF647

• UNSPSC Description:

  EZH2-AF647 is a fluorescent probe derived from UNC2239 that improves receptor TR-FRET properties by using Alexa 647 dye[1].

• Target Antigen:

  Fluorescent Dye

• Type:

  Dye Reagents

• Related Pathways:

  Others

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/ezh2-af647.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(N1)=CC(CCC)=C(CNC(C2=C(C=NN3C(C)C)C3=CC(C4=CC=C(N5CCN(CCCCNC(CCCCCN6C7=CC=C(S(=O)([O-])=O)C=C7C(C)(C)/C6=C/C=C/C=C/C8=[N+](CCOC)C9=CC=C(S(=O)(O)=O)C=C9C8(C)C)=O)CC5)N=C4)=C2)=O)C1=O

• Molecular Weight:

  1267.60

• References & Citations:

  [1]Falkenstern L, et al., A miniaturized mode-of-action profiling platform enables high throughput characterization of the molecular and cellular dynamics of EZH2 inhibition. Sci Rep. 2024 Jan 19;14(1):1739.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported