EZH2-IN-4
CAT:
804-HY-139150
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
EZH2-IN-4
- CAS Number: 2088132-99-2
- UNSPSC Description: EZH2-IN-4 is an orally active, potent EZH2 inhibitor with IC50s of 0.923 nM and 2.65 nM against wild type (WT) 5-membered (5-mer) EZH2 and mutant 5-mer EZH2, respectively. EZH2-IN-4 has anti-cancer activity[1].
- Target Antigen: Histone Methyltransferase
- Type: Reference compound
- Related Pathways: Epigenetics
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/ezh2-in-4.html
- Solubility: 10 mM in DMSO
- Smiles: CC1=C([C@@H]([C@@]2([H])CC[C@@](N3CC(C3)OC)([H])CC2)C)SC(CCCN4CC5=C(C=C(NC5=O)C)C)=C1C4=O
- Molecular Weight: 511.72
- References & Citations: [1]Esteban DOMINGUEZ, et al. Inhibitors of ezh2. WO2017035060A1.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported