EZH2-IN-5

• Description :

  EZH2-IN-5 is a potent EZH2 inhibitor with IC50 values of 1.52 nM and 4.07 nM for wild-type and mutant Tyr641 EZH2, respectively[1].

• CAS Number :

  [1403258-69-4]

• UNSPSC :

  12352005

• Target :

  Histone Methyltransferase

• Type :

  Reference compound

• Related Pathways :

  Epigenetics

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/ezh2-in-5.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CCN([C@H]1CC[C@@H](CC1)N(C)C)C2=C(C(C(NCC3=C(C=C(NC3=O)C)C)=O)=CC(Br)=C2)C

• Molecular Formula :

  C26H37BrN4O2

• Molecular Weight :

  517.50

• References & Citations :

  [1]Richard Chesworth, et al. Substituted benzene compounds. WO2012142513A1

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  EZH2