EZH2-IN-2

• UNSPSC Description:

  EZH2-IN-2 is a EZH2 inhibitor extracted from patent WO2018133795A1, Compound Example 69, with an IC50 of 64 nM. EZH2-IN-2 can be used for the research of cancer or precancerous condition related to EZH2 activity[1].

• Target Antigen:

  Histone Methyltransferase

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/ezh2-in-2.html

• Purity:

  99.60

• Solubility:

  DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  O=C(NCC1=C(C)C=C(C)NC1=O)C2=CC(C3=CC=C(N4CCN(CC5CC5)CC4)N=C3C)=CC(N(C(C6CC6)=O)CC)=C2C

• Molecular Weight:

  610.79

• References & Citations:

  [1]LIU, Qing Song, et al. Ezh2 inhibitor and use thereof. WO2018133795A1.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  2238821-31-1