KR-60436

• Description:

  KR-60436 is a reversible H+/K+-ATPase inhibitor. KR-60436 can potently inhibit the metabolism of CYP1A2 substrates[1].

• UNSPSC:

  12352005

• Target:

  Proton Pump

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/kr-60436.html

• Smiles:

  FC (F) (F) OC1=C2N=C (C3=C (C2=CC=C1) N (CC3) C4=CC=C (C=C4C) OC) NCCO

• Molecular Formula:

  C22H22F3N3O3

• Molecular Weight:

  433.42

• References & Citations:

  [1]Ji HY, et al. Characterization of human liver cytochrome P450 enzymes involved in the metabolism of a new H+/K+-ATPase inhibitor KR-60436. Toxicol Lett. 2005 Jan 15;155 (1) :103-14.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  220853-65-6