KR-60436

• Description :

  KR-60436 is a reversible H+/K+-ATPase inhibitor. KR-60436 can potently inhibit the metabolism of CYP1A2 substrates[1].

• UNSPSC :

  12352005

• Target :

  Proton Pump

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/kr-60436.html

• Smiles :

  FC(F)(F)OC1=C2N=C(C3=C(C2=CC=C1)N(CC3)C4=CC=C(C=C4C)OC)NCCO

• Molecular Formula :

  C22H22F3N3O3

• Molecular Weight :

  433.42

• References & Citations :

  [1]Ji HY, et al. Characterization of human liver cytochrome P450 enzymes involved in the metabolism of a new H+/K+-ATPase inhibitor KR-60436. Toxicol Lett. 2005 Jan 15;155 (1) :103-14.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [220853-65-6]