KR-31080

• Description:

  KR-31080 is an derivative of imidazo [4,5-b] pyridine. KR-31080 inhibits angiotensin II receptor. KR-31080 inhibits the NO production in LPS-stimulated BV-2 cells at a concentration of 2 μm with inhibition of 8.3%[1].

• Product Name Alternative:

  SK-1080

• UNSPSC:

  12352005

• Target:

  Angiotensin Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/kr-31080.html

• Smiles:

  O=N1=C(C2=CC3=C(N=C2C)N(CC4=CC=C(C5=C(C6=NN=NN6)C=CC=C5)C=C4)C(CCCC)=N3)C=CC=C1

• Molecular Formula:

  C30H28N8O

• Molecular Weight:

  516.60

• References & Citations:

  [1]Jiyeon Ock, et al. A novel anti-neuroinflammatory pyridylimidazole compound KR-31360. Biochem Pharmacol. 2010 Feb 15;79 (4) :596-609.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [174800-22-7]