KR-40795

CAT: 0804-HY-169300Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-169300Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KR-40795 is a potent inhibitor of ATX (autotaxin), with the IC50 of 0.13 μM. KR-40795 plays an important role for liver diseases[1].
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/kr-40795.html
Smiles
O=C1C/C(C(N1C2=CC(Cl)=CC=C2)=O)=C/C3=CC=CC=C3OCC4=CC=C(C=C4)C(OC)=O
Molecular Formula
C26H20ClNO5
Molecular Weight
461.89
References & Citations
[1]Seung Hyeong Lee, et al. Design, synthesis and evaluation of 3- (2- (substituted benzyloxy) benzylidene) pyrrolidine-2,5-dione derivatives for novel ATX inhibitor. Bioorg Med Chem Lett. 2024 Oct 28:114:130006.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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