KR-40795

• Description:

  KR-40795 is a potent inhibitor of ATX (autotaxin), with the IC50 of 0.13 μM. KR-40795 plays an important role for liver diseases[1].

• UNSPSC:

  12352005

• Target:

  Phosphodiesterase (PDE)

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/kr-40795.html

• Smiles:

  O=C1C/C (C (N1C2=CC (Cl) =CC=C2) =O) =C/C3=CC=CC=C3OCC4=CC=C (C=C4) C (OC) =O

• Molecular Formula:

  C26H20ClNO5

• Molecular Weight:

  461.89

• References & Citations:

  [1]Seung Hyeong Lee, et al. Design, synthesis and evaluation of 3- (2- (substituted benzyloxy) benzylidene) pyrrolidine-2,5-dione derivatives for novel ATX inhibitor. Bioorg Med Chem Lett. 2024 Oct 28:114:130006.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported