KR-27425

• Description :

  AChE activator 1 (compound 13) is a non-pyridinium oxime reactivator of paraoxon-inhibited acetylcholinesterase (AChE) [1].

• UNSPSC :

  12352211

• Target :

  Endogenous Metabolite

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/kr-27425.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC(CCCNCCNC(/C=N/O)=O)C

• Molecular Formula :

  C10H21N3O2

• Molecular Weight :

  215.29

• References & Citations :

  [1]Vishakantegowda AG, et al. Discovery of (E) -2- (hydroxyimino) -N- (2 ((4methylpentyl) amino) ethyl) acetamide (KR-27425) as a non-pyridinium oxime reactivator of paraoxon-inhibited acetylcholinesterase [published online ahead of print, 2023 Oct 12]. Bioorg Med Chem Lett. 2023;96:129504.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported