PPC-NB

• Description:

  PPC-NB is a glutathione cleavable linker used for the antibody-drug conjugate (ADC) [1].

• UNSPSC:

  12352203

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  ADC Linker

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer; Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/ppc-nb.html

• Purity:

  99.90

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C (OCC (SSC1=NC=CC=C1) C) OC2=CC=C ([N+] ([O-]) =O) C=C2

• Molecular Formula:

  C15H14N2O5S2

• Molecular Weight:

  366.41

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Robert A. Volkmann, et al. Compounds, compositions, and methods for treatment of diseases involving acidic or hypoxic diseased tissues. WO2019136298A1.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  ADC Related

• Clinical Information:

  No Development Reported

• Isoform:

  Disulfide Cleavable Linker

• CAS Number:

  1887040-81-4