PPC-NB

• Description :

  PPC-NB is a glutathione cleavable linker used for the antibody-drug conjugate (ADC) [1].

• UNSPSC :

  12352203

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  ADC Linker

• Type :

  ADC Related

• Related Pathways :

  Antibody-drug Conjugate/ADC Related

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer; Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/ppc-nb.html

• Purity :

  99.90

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=C(OCC(SSC1=NC=CC=C1)C)OC2=CC=C([N+]([O-])=O)C=C2

• Molecular Formula :

  C15H14N2O5S2

• Molecular Weight :

  366.41

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Robert A. Volkmann, et al. Compounds, compositions, and methods for treatment of diseases involving acidic or hypoxic diseased tissues. WO2019136298A1.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  ADC Related

• Clinical Information :

  No Development Reported

• Isoform :

  Disulfide Cleavable Linker

• CAS Number :

  [1887040-81-4]