RegisterLogin

Ppc-1

CAT: 0804-HY-117843Size: 1 EachDry Ice: NoHazardous: No
CAT#: HY-117843Size: 1 Each
Selected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Ppc-1 is a mitochondrial uncoupler. Ppc-1 enhances mitochondrial oxygen consumption without adverse effects on ATP production. Ppc-1 is a cell-permeate interleukin-2 (IL-2) inhibitor. Ppc-1 inhibits the Gram-negative periodontopathogen Porphyromonas gingivalis. Ppc-1 has anti-obesity, antibacterial and anti-inflammatory activities[1][2][3][4].
CAS Number
[1245818-17-0]
UNSPSC
12352005
Target
Bacterial; Interleukin Related; Mitochondrial Metabolism
Type
Reference compound
Related Pathways
Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Infection; Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ppc-1.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=NC2=C(OC/C=C(C)/C)C=CC=C2C(OC)=C1)OC/C=C(C)\C
Molecular Formula
C21H25NO4
Molecular Weight
355.43
References & Citations
[1]Suzuki T, et al. Weight loss by Ppc-1, a novel small molecule mitochondrial uncoupler derived from slime mold. PLoS One. 2015 Feb 10;10 (2) :e0117088.|[2]Ogura M, et al. Prenylated quinolinecarboxylic acid derivative suppresses immune response through inhibition of PAK2. Biochem Pharmacol. 2016 Apr 1;105:55-65.|[3]Haruhisa Kikuchi a, et al. Novel prenylated and geranylated aromatic compounds isolated from Polysphondylium cellular slime molds. Tetrahedron 66 (2010) 6000-6007.|[4]Azelmat J, et al. Antibacterial and Anti-inflammatory Activities of Ppc-1, Active Principle of the Cellular Slime Mold Polysphondylium pseudo-candidum. Med Chem. 2015;11 (7) :666-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IL-2

Related Products

CatalogName
HY-126530-01PPC-NB
HY-W071006-01PPC-NHS ester
HY-P71222-01PPC-DC, Human (His)
HY-P71222A-01PPC-DC, Human (His, solution)
HY-111081(±) -PPCC
HY-N6838-011,1,1,1-Kestohexaose
HY-157129AMPK-α1β1γ1 activator 1
HY-1336231,1,1-Tribromoacetone
HY-108514(±) -PPCC (hemioxalate)
HY-111081C-01(±) -PPCC (oxalate)

Alternative Products

CatalogName
MBS5769791Ppc-1
T16565-01Ppc-1
T18558-01PPC-NB
BA2438-50PPC-NB
MBS5771417PPC-NB
BA2438-250PPC-NB
BA2438-100PPC-NB
MBS5771418PPC-NHS ester
T18559PPC-NHS ester
OR1005518PPC-NHS ester

Popular Products