PDdEC-NB

• Description :

  PDdEC-NB is a disulfide cleavable linker used for the antibody-drug conjugate (ADC) .

• UNSPSC :

  12352203

• Hazard Statement :

  H302-H315-H319-H335

• Target :

  ADC Linker

• Type :

  ADC Related

• Related Pathways :

  Antibody-drug Conjugate/ADC Related

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/pddec-nb.html

• Purity :

  97.63

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(OC1=CC=C([N+]([O-])=O)C=C1)OCC(SSC2=NC=CC=C2)(C)C

• Molecular Formula :

  C16H16N2O5S2

• Molecular Weight :

  380.44

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations :

  [1]Flygare, John, et al. Anthracycline disulfide intermediates, antibody-​drug conjugates and methods.WO 2016040825 A1 20160317.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  ADC Related

• Clinical Information :

  No Development Reported

• Isoform :

  Cleavable Linker; Disulfide Cleavable Linker

• CAS Number :

  [1956318-90-3]