Nb-Demethylechitamine

Nb-Demethylechitamine

• CAS Number: 60048-88-6
• UNSPSC Description: Nb-Demethylechitamine is an alkaloid isolated from the methanol extract of Alstonia rostrata twigs. Nb-Demethylechitamine has in vitro cytotoxic activity against several human cancer cell lines, including human myeloid leukemia HL-60, liver cancer SMMC-7721, lung cancer A-549, breast cancer MCF-7, and colon cancer SW480 cells[1].
• Target Antigen: Others
• Type: Natural Products
• Related Pathways: Others
• Applications: Cancer-programmed cell death
• Field of Research: cancer
• Assay Protocol: https://www.medchemexpress.com/nb-demethylechitamine.html
• Solubility: 10 mM in DMSO
• Smiles: C/C=C(C1)\[C@@H]2C[C@@H](O)[C@@]3([N@@]1CC4)[C@]4(C2(CO)C(OC)=O)C5=C(N3)C=CC=C5
• Molecular Weight: 370.44
• References & Citations: [1]Yuan YX, et al. Two new monoterpenoid indole alkaloids from Alstonia rostrata. Nat Prod Res. 2018 Apr;32(7):844-848.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported