Nb-Demethylechitamine

• UNSPSC Description:

  Nb-Demethylechitamine is an alkaloid isolated from the methanol extract of Alstonia rostrata twigs. Nb-Demethylechitamine has in vitro cytotoxic activity against several human cancer cell lines, including human myeloid leukemia HL-60, liver cancer SMMC-7721, lung cancer A-549, breast cancer MCF-7, and colon cancer SW480 cells[1].

• Target Antigen:

  Others

• Type:

  Natural Products

• Related Pathways:

  Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  cancer

• Assay Protocol:

  https://www.medchemexpress.com/nb-demethylechitamine.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C/C=C(C1)\[C@@H]2C[C@@H](O)[C@@]3([N@@]1CC4)[C@]4(C2(CO)C(OC)=O)C5=C(N3)C=CC=C5

• Molecular Weight:

  370.44

• References & Citations:

  [1]Yuan YX, et al. Two new monoterpenoid indole alkaloids from Alstonia rostrata. Nat Prod Res. 2018 Apr;32(7):844-848.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  60048-88-6