PROTAC RIPK degrader-6

PROTAC RIPK degrader-6

• CAS Number: 2089205-64-9
• UNSPSC Description: PROTAC RIPK degrader-6 (example 1) is a Cereblon-based PROTAC targeting RIP Kinase degradation wherein the RIP2 kinase inhibitor is linked via a linker to a cereblon binder[1].
• Target Antigen: PROTACs; RIP kinase
• Type: Reference compound
• Related Pathways: Apoptosis;PROTAC
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/protac-ripk-degrader-6.html
• Purity: 99.97
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O=S(C(C(OCCOCCOCCOCCOCC(NC1=C(CN(C2C(NC(CC2)=O)=O)C3=O)C3=CC=C1)=O)=C4)=CC(C4=NC=C5)=C5NC6=CC(N=CS7)=C7C=C6)(C(C)(C)C)=O
• Molecular Weight: 889.00
• References & Citations: [1]John David Harlin, et al. Compounds for the modulation of rip2 kinase activity. WO2017046036A1.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported