PROTAC BRD9 Degrader-6

• CAS Number:

  2676211-62-2

• UNSPSC Description:

  PROTAC BRD9 Degrader-6 is a potent degrader of BRD9 (IC50=0.13 nM), can be used for research of BAF complex-related disorders[1].

• Target Antigen:

  Epigenetic Reader Domain; PROTACs

• Type:

  Reference compound

• Related Pathways:

  Epigenetics;PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/protac-brd9-degrader-6.html

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C1C2=C(C(C3=CC(OC)=C(CN4CCC(CC4)CN5CCC6(CC5)CN(C6)C7=CC=C8C(C(N(C9C(NC(CC9)=O)=O)C8)=O)=C7)C(OC)=C3)=CN1C)C=C(N%10CCC%10)N=C2

• Molecular Weight:

  829.00

• References & Citations:

  [1]Ruppel Sabine K, et al. Preparation of substituted naphthyridines for treating BAF complex-related disorders. United States, US20210230190 A1. 2021-07-29.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported