PROTAC BRD9 Degrader-6

PROTAC BRD9 Degrader-6

• CAS Number: 2676211-62-2
• UNSPSC Description: PROTAC BRD9 Degrader-6 is a potent degrader of BRD9 (IC50=0.13 nM), can be used for research of BAF complex-related disorders[1].
• Target Antigen: Epigenetic Reader Domain; PROTACs
• Type: Reference compound
• Related Pathways: Epigenetics;PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/protac-brd9-degrader-6.html
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O=C1C2=C(C(C3=CC(OC)=C(CN4CCC(CC4)CN5CCC6(CC5)CN(C6)C7=CC=C8C(C(N(C9C(NC(CC9)=O)=O)C8)=O)=C7)C(OC)=C3)=CN1C)C=C(N%10CCC%10)N=C2
• Molecular Weight: 829.00
• References & Citations: [1]Ruppel Sabine K, et al. Preparation of substituted naphthyridines for treating BAF complex-related disorders. United States, US20210230190 A1. 2021-07-29.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported