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BuChE-IN-15

CAT: 0804-HY-168563Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-168563Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BuChE-IN-15 (compound D12) is a selective BuChE/FAAH dual inhibitor with and show IC50 values of 81 and 400 nM for hBuChE and hFFAH, respectively. BuChE-IN-15 possesses good BBB penetration, and shows neuroprotection.BuChE-IN-15 can be used for study of Alzheimer[1].
UNSPSC
12352101
Target
Cholinesterase (ChE) ; FAAH
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/buche-in-15.html
Smiles
COC1=CC=C(C(C(C)=O)=C1)OC(N(CC2=CC=C(C=C2)F)C)=O
Molecular Formula
C18H18FNO4
Molecular Weight
331.34
References & Citations
[1]Rong K, et al. Natural phenol carbamates: Selective BuChE/FAAH dual inhibitors show neuroprotection in an Alzheimer's disease mouse model. Eur J Med Chem. Published online October 28, 2024.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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