BuChE-IN-3

• Description:

  BuChE-IN-3 (Compound C4) is a potent inhibitor of BuChE with an IC50 of 8.3 nM. BuChE-IN-3 exhibits mild antioxidant capacity, nontoxicity, lipophilicity and neuroprotective activity[1].

• UNSPSC:

  12352005

• Target:

  Cholinesterase (ChE)

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/buche-in-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=S1(CCC2=C(N(N=C2CN(CC3=CC=C(C=C3)F)CCO)C4=CC=CC=C4F)O1)=O

• Molecular Formula:

  C21H21F2N3O4S

• Molecular Weight:

  449.47

• References & Citations:

  [1]Zhang Z, et al. The structure-based optimization of δ-sultone-fused pyrazoles as selective BuChE inhibitors. Eur J Med Chem. 2020 Sep 1;201:112273.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  BChE

• CAS Number:

  [2499488-78-5]