BuChE-IN-3

• Description :

  BuChE-IN-3 (Compound C4) is a potent inhibitor of BuChE with an IC50 of 8.3 nM. BuChE-IN-3 exhibits mild antioxidant capacity, nontoxicity, lipophilicity and neuroprotective activity[1].

• CAS Number :

  [2499488-78-5]

• UNSPSC :

  12352005

• Target :

  Cholinesterase (ChE)

• Type :

  Reference compound

• Related Pathways :

  Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/buche-in-3.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=S1(CCC2=C(N(N=C2CN(CC3=CC=C(C=C3)F)CCO)C4=CC=CC=C4F)O1)=O

• Molecular Formula :

  C21H21F2N3O4S

• Molecular Weight :

  449.47

• References & Citations :

  [1]Zhang Z, et al. The structure-based optimization of δ-sultone-fused pyrazoles as selective BuChE inhibitors. Eur J Med Chem. 2020 Sep 1;201:112273.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  BChE