BuChE-IN-7

CAT: 0804-HY-152632Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-152632Size:1 Each
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Description
BuChE-IN-7 is a highly selective inhibitor of hBuChe and eqBuChE with IC50 values of 40 nM, 80 nM respectively. BuChE-IN-7 can promote cognitive with blood-brain penetration and improves situational and phobic memory, showing preference for new things[1].
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/buche-in-7.html
Solubility
10 mM in DMSO
Smiles
O=C(CC(C1=CC=CC=C1)C2=CC=CC=C2)NC[C@H](O)CNCC3CCCCC3
Molecular Formula
C25H34N2O2
Molecular Weight
394.55
References & Citations
[1]Panek D, et al. Discovery of new, highly potent and selective inhibitors of BuChE - design, synthesis, in vitro and in vivo evaluation and crystallography studies. Eur J Med Chem. 2023 Jan 18;249:115135.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
BChE

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