Me-IQ

• Description :

  Me-IQ (Methyl-IQ), an orally active heterocyclic amine, is carcinogenic and mutagenic. Me-IQ is several hundred-fold more mutagenic in liver than in lung microsomal preparations from uninduced mice and rabbits[1][2].

• Product Name Alternative :

  Methyl-IQ

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Biochemical Assay Reagents

• Type :

  Reference compound

• Related Pathways :

  Others

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/me-iq.html

• Purity :

  99.48

• Solubility :

  DMSO : 50 mg/mL (ultrasonic)

• Smiles :

  NC(N1C)=NC2=C1C(C)=CC3=C2C=CC=N3

• Molecular Formula :

  C12H12N4

• Molecular Weight :

  212.25

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]H Ohgaki, et al. Carcinogenicities in mice and rats of IQ, MeIQ, and MeIQx. Princess Takamatsu Symp. 1985;16:97-105.|[2]T Aune, et al. Mutagenic activation of IQ and Me-IQ by liver and lung microsomes from rabbit and mouse, and with isolated lung cells from the rabbit. Carcinogenesis. 1986 Feb;7 (2) :273-6.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [77094-11-2]