Me-Indoxam

CAT: 0804-HY-125157Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-125157Size:1 Each
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Description
Me-Indoxam is a potent and cell-impermeable secreted phospholipase A2 (sPLA2) inhibitor[1].
CAS Number
[172732-62-6]
UNSPSC
12352005
Target
Phospholipase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/me-indoxam.html
Solubility
10 mM in DMSO
Smiles
O=C(COC1=CC=CC2=C1C(C(C(N)=O)=O)=C(N2CC3=CC=CC=C3C4=CC=CC=C4)C)O
Molecular Formula
C26H22N2O5
Molecular Weight
442.46
References & Citations
[1]Triggiani M, et al. Lung mast cells are a source of secreted phospholipases A2. J Allergy Clin Immunol. 2009 Sep;124 (3) :558-65, 565.e1-3.|[2]Granata F, et al. Activation of cytokine production by secreted phospholipase A2 in human lung macrophages expressing the M-type receptor. J Immunol. 2005 Jan 1;174 (1) :464-74.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Phospholipase A

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