Me-Indoxam

• Description :

  Me-Indoxam is a potent and cell-impermeable secreted phospholipase A2 (sPLA2) inhibitor[1].

• UNSPSC :

  12352005

• Target :

  Phospholipase

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/me-indoxam.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(COC1=CC=CC2=C1C(C(C(N)=O)=O)=C(N2CC3=CC=CC=C3C4=CC=CC=C4)C)O

• Molecular Formula :

  C26H22N2O5

• Molecular Weight :

  442.46

• References & Citations :

  [1]Triggiani M, et al. Lung mast cells are a source of secreted phospholipases A2. J Allergy Clin Immunol. 2009 Sep;124 (3) :558-65, 565.e1-3.|[2]Granata F, et al. Activation of cytokine production by secreted phospholipase A2 in human lung macrophages expressing the M-type receptor. J Immunol. 2005 Jan 1;174 (1) :464-74.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Phospholipase A

• CAS Number :

  [172732-62-6]