Me-Indoxam

• Description:

  Me-Indoxam is a potent and cell-impermeable secreted phospholipase A2 (sPLA2) inhibitor[1].

• UNSPSC:

  12352005

• Target:

  Phospholipase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/me-indoxam.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C (COC1=CC=CC2=C1C (C (C (N) =O) =O) =C (N2CC3=CC=CC=C3C4=CC=CC=C4) C) O

• Molecular Formula:

  C26H22N2O5

• Molecular Weight:

  442.46

• References & Citations:

  [1]Triggiani M, et al. Lung mast cells are a source of secreted phospholipases A2. J Allergy Clin Immunol. 2009 Sep;124 (3) :558-65, 565.e1-3.|[2]Granata F, et al. Activation of cytokine production by secreted phospholipase A2 in human lung macrophages expressing the M-type receptor. J Immunol. 2005 Jan 1;174 (1) :464-74.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  Phospholipase A

• CAS Number:

  172732-62-6