IQ-1S

• Target:

  JNK

• Related Pathways:

  MAPK

• Bioactivity:

  IQ-1S is an inhibitor of NF-?B/activating protein 1 (AP-1) with an IC50 of 1.8 ?M. It exhibits high binding affinity to all three JNKs, with Kd values for JNK3, JNK2, and JNK1 being 87 nM, 360 nM, and 390 nM, respectively.

• Smiles:

  [O-]N=C1C2=C(C3=CC=CC=C13)N=C4C=CC=CC4=N2.[Na+]

• Molecular Formula:

  C15H8N3NaO

• Molecular Weight:

  269.23

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1421610-21-0