Products for Research Use Only
RegisterLogin

HDAC8-IN-10

CAT: 0804-HY-163846Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-163846Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
HDAC8-IN-10 (compound 15) is a potent inhibitor of HDAC8, with the IC50 of 7.6 nM. HDAC8-IN-10 is a HDAC8 target protein ligand that can be used to synthesize PROTAC YX862.
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hdac8-in-10.html
Smiles
CCCCCCNNC(C(C=C1)=CC=C1N2CCN(C)CC2)=O
Molecular Formula
C18H30N4O
Molecular Weight
318.46
References & Citations
[1]Yufeng Xiao, et al. Discovery of a Highly Potent and Selective HDAC8 Degrader: Advancing the Functional Understanding and Therapeutic Potential of HDAC8. J Med Chem. 2024 Jul 1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC8

Related Products

CatalogName
HY-161465HDAC8-IN-7
HY-153583HDAC8-IN-4
HY-149529HDAC8-IN-5
HY-161954HDAC8-IN-12
HY-144098HDAC8-IN-2
HY-147934HDAC8-IN-3
HY-163921HDAC8-IN-11
HY-111027HDAC8-IN-13
HY-163143HDAC8-IN-6
HY-111342-01HDAC8-IN-1

Alternative Products

CatalogName
T89475-01HDAC8-IN-10
sc-56687HDAC8 (HDAC8-48)
318450-01HDAC8
GTR17881854-01HDAC8 Antibody
A4613-10HDAC8-IN-1
T209650-01HDAC8-IN-7
AF6481-BPHDAC8 Peptide

Popular Products