Products for Research Use Only
RegisterLogin

HDAC8-IN-6

CAT: 0804-HY-163143Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-163143Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
HDAC8-IN-6 (compound 3) is a potent HDAC8 inhibitor with an IC50 of 5.1 μM. HDAC8-IN-6 shows cytotoxicity[1].
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hdac8-in-6.html
Solubility
10 mM in DMSO
Smiles
C[N+]1=CC=C(NC(CC(N2CC3=C(C=CC=C3)C2)=O)=O)C(C#C)=C1.[I-]
Molecular Formula
C19H18IN3O2
Molecular Weight
447.27
References & Citations
[1]Keeley AB, et al. Electrophilic MiniFrags Revealed Unprecedented Binding Sites for Covalent HDAC8 Inhibitors. J Med Chem. 2024 Jan 11;67 (1) :572-585.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC4; HDAC8

Related Products

CatalogName
HY-163846HDAC8-IN-10
HY-161465HDAC8-IN-7
HY-153583HDAC8-IN-4
HY-149529HDAC8-IN-5
HY-161954HDAC8-IN-12
HY-163921HDAC8-IN-11
HY-144098HDAC8-IN-2
HY-147934HDAC8-IN-3
HY-111027HDAC8-IN-13
HY-111342-01HDAC8-IN-1

Alternative Products

CatalogName
GTR19261795-01HDAC8-IN-6
sc-56687HDAC8 (HDAC8-48)
PVT57130pT7-6×His-HDAC8 Plasmid
CSB-CL010244HUHDAC8
CSB-PA010244GA01HUHDAC8 Antibody
A4613-10HDAC8-IN-1
T209650-01HDAC8-IN-7
AF6481-BPHDAC8 Peptide

Popular Products